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Zinecard IV

Generic Name: DEXRAZOXANE - INJECTION
Pronounced: (dex-razz-OX-ane)

Zinecard IV Side Effects

Because this medication is used with another medication, it is difficult to tell which side effects are caused by dexrazoxane. Nausea, vomiting, loss of appetite, trouble swallowing, diarrhea, temporary hair loss, or pain/irritation at the injection site have been reported. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

When combined with chemotherapy, dexrazoxane may worsen the effects that these medications can have on your bone marrow. Tell your doctor right away if you have any serious side effects, including:

  • unusual weakness
  • mouth sores
  • signs of infection (e.g., fever, persistent sore throat)
  • easy bruising/bleeding


Very rarely, people with cancer who have been treated with this medication have developed other cancers (e.g., leukemia, lymphoma). Consult your doctor for more details.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Zinecard IV Precautions

Before using dexrazoxane, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • kidney disease


During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.

This drug passes into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Zinecard IV Medical Alert

Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

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