Lomefloxacin Oral
In Depth
This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.
Based on information from related drugs, this medication may pass into breast milk. Therefore, breast-feeding while using this medication is not recommended. Consult your doctor before breast-feeding.
Lomefloxacin Oral Drug Interactions
See also How to Use section.
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious interactions may occur:
- certain antiarrhythmics (e.g., quinidine, procainamide, amiodarone, dofetilide, sotalol)
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.
Other drugs besides this medication and those listed above which may affect the heart rhythm (QTc prolongation in the EKG) include cisapride, erythromycin, and antipsychotics ( e.g., pimozide) among others. QTc prolongation can infrequently result in serious, rarely fatal, irregular heartbeats. Consult your doctor or pharmacist for more details, and for instructions on how you may minimize the risk of this effect.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:
- corticosteroids (e.g., prednisone, hydrocortisone)
- cyclosporine
- NSAIDs (e.g., ibuprofen, naproxen)
- probenecid
- live bacterial vaccines
- drugs that lower potassium levels (e.g., diuretics such as furosemide)
- warfarin
Also report to your doctor the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with this medication, such as phenothiazines (e.g., thioridazine), tricyclic antidepressants (e.g., amitriptyline), isoniazid (INH), and theophylline, among others. Consult your doctor or pharmacist for details.


