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Ifosfamide IV

Generic Name: IFOSFAMIDE - INJECTION
Pronounced: (eye-FOSS-fuh-mide)

Ifosfamide IV Warning

Ifosfamide may cause serious side effects (e.g., urinary problems such as hemorrhagic cystitis, mental/mood changes, and blood/bone marrow disorders), which may require your treatment with this medication to be stopped. Tell your doctor immediately if you develop symptoms such as pink/bloody urine, frequent/painful urination, severe drowsiness, confusion, or hallucinations. Blood/bone marrow disorders can affect your body's ability to stop bleeding or fight infection. Tell your doctor immediately if you develop easy bruising/bleeding or signs of infection (e.g., fever, chills, persistent sore throat).

Ifosfamide IV Side Effects

See also Warning section.

Nausea, vomiting, diarrhea, stomach/abdominal pain, loss of appetite, or redness/pain/swelling at the injection site may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If these effects persist or worsen, tell your doctor or pharmacist promptly.

Severe nausea, vomiting, and diarrhea may infrequently result in a loss of too much body water (dehydration). Contact your doctor promptly if you notice any symptoms of dehydration such as unusual decreased urination, unusual dry mouth/increased thirst, lack of tears, dizziness/lightheadedness, or pale/wrinkled skin.

Temporary hair loss frequently occurs in patients using this drug. Normal hair growth should return after treatment has ended.

Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • unusual weakness
  • seizure


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction:

  • rash
  • itching
  • swelling
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Ifosfamide IV Medical Alert

Your condition can cause complications in a medical emergency. For information about enrolling in MedicAlert, call 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

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