Hycamtin IV
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (TOE-poe-TEE-kan)
Hycamtin IV Warning
Topotecan may cause very serious (possibly fatal) blood disorders (decreased bone marrow function leading to low number of blood cells such as white cells, red cells, and platelets). This effect can decrease your body's ability to fight an infection, cause your body to bruise or bleed easier, or cause anemia. Tell your doctor if you develop any of the following conditions: signs of an infection (such as fever, persistent sore throat), easy bruising/bleeding, unusual tiredness, fast/pounding heartbeat.
You will be closely monitored (e.g., with frequent blood tests) by your doctor while using this medication. Keep all medical and laboratory appointments.
Hycamtin IV Side Effects
See also Warning section.
Weakness, tiredness, headache, cough, nausea, vomiting, diarrhea, constipation, abdominal pain, loss of appetite, and mouth sores may occur. Nausea and vomiting can be severe. In some cases, your doctor may prescribe medication to prevent or relieve nausea and vomiting. Eating several small meals, not eating before treatment, or limiting activity may help lessen some of these effects. If these effects persist or worsen, tell your doctor or pharmacist promptly.
Temporary hair loss may occur. Normal hair growth should return after treatment has ended.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including:
- pain/redness/bruising at injection site
- numbness/tingling of the arms/legs
- yellowing eyes/skin
- dark urine
- lung problems (such as cough, shortness of breath)
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including:
- rash
- itching/swelling (especially of the face/tongue/throat)
- severe dizziness
- trouble breathing
Previous Section

