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Coumadin Oral

Generic Name: WARFARIN - ORAL
Pronounced: (WARF-uh-rin)

Coumadin Oral Warning

Warfarin can cause serious, possibly fatal bleeding, which is more likely to occur when patients first start this medication and/or when taking too high of a dose. The risk is greater in patients older than 65 years and in those with major injuries/surgeries, previous stomach/intestinal bleeding, or stroke. Your doctor or other healthcare provider will monitor you closely to decrease your risk. Keep all medical/lab appointments. (See also Precautions section.)

Coumadin Oral Side Effects

Nausea, loss of appetite, stomach/abdominal bloating, or cramps may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication can cause serious bleeding if it affects your blood clotting proteins too strongly (unusually high PT and INR lab results). Even if your doctor stops your medication, this risk can continue for up to a week. Tell your doctor immediately if you have any signs of serious bleeding, including:

  • unusual pain/swelling/discomfort
  • severe headache
  • dizziness/fainting
  • unusual or persistent tiredness/weakness
  • bloody/black/tarry stools
  • unusual or easy bruising
  • prolonged bleeding from cuts or gums
  • persistent/frequent nosebleeds
  • unusually heavy/prolonged menstrual flow
  • pink/dark urine
  • coughing up blood
  • vomit that is bloody or looks like coffee grounds
  • fast/pounding heartbeat
  • chest pain
  • shortness of breath
  • difficulty swallowing


This drug may very rarely cause serious, possibly fatal skin/tissue damage. Patients with certain blood conditions (protein C or S deficiency) may be at greater risk. If left untreated, this effect can lead to severe tissue damage (necrosis, gangrene) that requires surgery or amputation. Seek immediate medical attention if any of these very rare but serious side effects occur:

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