Tacrolimus Oral

Tacrolimus Oral Warning

Tacrolimus lowers the body's ability to fight an infection/disease (immunosuppression). This may increase your risk of developing an infection or certain types of cancer (e.g., skin cancer, lymphoma). To reduce the risk of these serious side effects, take this medication at the lowest effective dose as directed by your doctor. Keep all medical and laboratory appointments.

Tell your doctor immediately if you develop any of the following: unusual skin changes, change in the appearance/size of moles, unusual growths/lumps, swollen glands, night sweats, unexplained weight loss, signs of infection (e.g., fever, persistent sore throat).

Tacrolimus Oral Side Effects

See also Warning section.

Shaking, headache, diarrhea, nausea/vomiting, upset stomach, loss of appetite, trouble sleeping, or tingling of the hands/feet may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

• mental/mood changes
• seizures
• dizziness
• change in the amount of urine
• tiredness/weakness
• fast/pounding heartbeat
• hearing problems (e.g., hearing loss, ringing in the ears)
• pain/redness/swelling of arms or legs
• easy bruising/bleeding
• muscle pain/cramp
• yellowing skin/eyes
• dark urine
• persistent nausea/vomiting
• stomach/abdominal pain
• swelling ankles/feet

Seek immediate medical attention if any of these rare but very serious side effects occur:

• fainting
• irregular heartbeat
• vision changes
• chest/jaw/left arm pain
• black stools
• vomit that looks like coffee grounds

Tacrolimus may cause your blood pressure to increase. You may be required to check your blood pressure periodically and/or take another medication to control your blood pressure.

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Drug Interactions

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Dosage and Storage

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