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Depo-Provera IM

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Depo-Provera IM Precautions

Before using medroxyprogesterone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • history of stroke or other blood clots (such as in the legs, eyes, lungs)
  • breast cancer
  • family history of breast cancer
  • abnormal breast exam
  • cancer of the cervix
  • abnormal/unexplained vaginal bleeding
  • liver disease
  • current/suspected pregnancy
  • depression
  • frequent use of alcohol/tobacco
  • asthma
  • diabetes
  • heart disease (such as chest pain, heart failure, high blood pressure)
  • kidney disease
  • migraine
  • seizures
  • personal/family history of bone disease (such as osteoporosis)


Before having surgery, tell your doctor or dentist about all of the products you use (including prescription drugs, nonprescription drug, and herbal products).

This medication must not be used during pregnancy. It may harm an unborn baby. If you become pregnant or think you may be pregnant, tell your doctor immediately.

This drug passes into breast milk. Consult your doctor before breast-feeding.

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