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BiCNU IV

In Depth

Generic Name: CARMUSTINE - INJECTION
Pronounced: (kar-MUST-een)

BiCNU IV Warning

This medication may cause very serious blood disorders (decreased bone marrow function leading to low number of blood cells such as red cells, white cells, and platelets). These effects can cause anemia, decrease your body's ability to fight an infection, or cause your body to bruise or bleed more easily. If these effects occur, it is usually 4 to 6 weeks after the medication is given. Your doctor will monitor your blood counts for at least 6 weeks after your dose of the medication. Tell your doctor immediately if you develop any of the following symptoms: signs of infection (e.g., fever, persistent sore throat), easy bruising/bleeding, unusual tiredness, fast/pounding heartbeat.

This medication may also cause very serious (possibly fatal) lung problems. The lung problems can occur years after treatment. Tell your doctor immediately if you develop any of the following symptoms: shortness of breath, persistent cough, chest pain, persistent weakness/tiredness.

BiCNU IV Side Effects

See also Warning section.

Nausea, vomiting, headache, flushing, or pain at injection site may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Many people using this medication have serious side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • dark urine
  • yellowing eyes/skin
  • severe stomach/abdominal pain
  • change in the amount of urine
  • vision changes
  • fast heartbeat
  • dizziness


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

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