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Amprenavir Oral

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Generic Name: AMPRENAVIR - ORAL
Pronounced: (am-PREN-a-vir)

Amprenavir Oral Warning

Amprenavir is known to interact with many different types of medicines, in some cases causing severe (sometimes fatal) reactions. Consult your doctor or pharmacist about which medications should not be taken with amprenavir. (See also Drug Interactions section.)

Amprenavir Oral Side Effects

See also Warning section.

Diarrhea, nausea, vomiting, heartburn, stomach pain, gas, loss of appetite, headache, tiredness, strange taste in the mouth, or tingling/numbness of hands/feet/mouth area may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • persistent nausea
  • stomach/abdominal pain
  • dark urine
  • yellowing eyes/skin
  • decreased sexual interest
  • mental/mood changes (e.g., depression, anxiety)
  • increasing tiredness
  • increased urination (especially at night)
  • increased thirst
  • fruity breath odor


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • severe tiredness
  • fainting
  • pale lips/nails/skin
  • fast heartbeat
  • fast breathing


Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.

If you are taking HIV medications for the first time, you may experience symptoms of an old infection. This may happen as your immune system begins to work better. Contact your doctor immediately if you notice any of the following symptoms:

  • new cough
  • trouble breathing
  • fever
  • new vision problems
  • new headaches
  • new skin problems
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