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VFEND IV IV

In Depth

Generic Name: VORICONAZOLE - INJECTION
Pronounced: (vor-ih-CON-ah-zole)

VFEND IV IV Side Effects

Nausea, vomiting, diarrhea, and headache may occur. If any of these effects persist or worsen, tell your doctor promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • vision changes (e.g., blurring, color vision changes)
  • sensitivity of eyes to light (photophobia)
  • pain/swelling at injection site
  • shortness of breath
  • flushing
  • increased sweating
  • bone/muscle/joint pain
  • weakness
  • muscle stiffness/spasm
  • mental/mood changes (e.g., agitation, restlessness)
  • swelling of the ankles/feet
  • tiredness
  • easy bleeding/bruising
  • signs of infection (e.g., fever, persistent sore throat)


Seek immediate medical attention if any of these rare but very serious side effects occur:

  • fast/slow/irregular heartbeat
  • severe dizziness
  • fainting
  • change in the amount of urine
  • confusion
  • slurred speech
  • trouble breathing
  • seizures
  • chest/jaw/left arm pain


Voriconazole may rarely cause serious (possibly fatal) liver problems. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur:

  • yellowing eyes/skin
  • dark urine
  • persistent nausea/vomiting
  • stomach/abdominal pain


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


Voriconazole can commonly cause a mild rash that is usually not serious. However, you may not be able to tell it apart from a rare rash that could be a sign of a severe allergic reaction. Therefore, seek immediate medical attention if you develop any rash.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Call your doctor for medical advice about side effects. In the US, you may report side effects to the Food and Drug Administration (FDA) at 1-800-FDA-1088.

In Canada, you may report side effects to Health Canada at 1-866-234-2345.

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