Tenofovir Disoproxil Fumarate Oral

In Depth

Generic Name: TENOFOVIR - ORAL
Pronounced: (te-NOE-fo-veer)

Tenofovir Disoproxil Fumarate Oral Warning

Rarely, tenofovir has caused a severe (sometimes fatal) liver and blood problem (lactic acidosis). Immediately tell your doctor if you develop symptoms of liver problems (persistent nausea, stomach/abdominal pain, dark urine, yellowing eyes/skin), or of lactic acidosis (rapid breathing, drowsiness, muscle aches).

If you have hepatitis B infection along with HIV, your hepatitis symptoms may get worse or become very serious if you stop taking tenofovir. Talk with your doctor before stopping this medication. Your doctor will perform liver function tests for several months after you stop tenofovir. Tell your doctor immediately if you develop symptoms of worsening liver problems.

Tenofovir Disoproxil Fumarate Oral Side Effects

See also Warning section.

Dizziness, nausea, diarrhea, stomach pain, gas, headache, trouble sleeping, loss of appetite, or weakness may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

mental/mood changes (e.g., depression, anxiety)
tingling/numbness of hands or feet

Tell your doctor immediately if any of these rare but very serious side effects occur:

bone pain
stomach/back pain with or without nausea/vomiting
muscle tenderness/pain/weakness
new fever
chills
cough
breathing problems
weight loss
new diarrhea
sore throat
pink/bloody urine
change in the amount of urine

Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.

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