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When this medication is used for a long time, it may not work as well. Different dosing may be required. Follow your doctor's instructions on how to use this product to decrease the risk that the medication will become less effective over time. Talk with your doctor if this medication stops working well.

Do not suddenly stop using this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Your dose may need to be gradually decreased.

Inform your doctor if your condition worsens (e.g., the number of angina attacks increases).

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