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Prazosin-Polythiazide Oral

In Depth



For males, in the very unlikely event you have a painful, prolonged erection (lasting more than 4 hours), stop using this drug and seek immediate medical attention or permanent problems could occur.

Tell your doctor immediately if any of these rare but very serious side effects occur:

  • severe or persistent nausea/vomiting
  • severe stomach pain
  • eye pain
  • yellowing skin/eyes
  • dark urine
  • signs of infection (e.g., fever, persistent sore throat)
  • easy bruising/bleeding


A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include:

  • rash
  • itching
  • swelling
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

Prazosin-Polythiazide Oral Medical Alert

Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA) or 1-800-668-1507 (Canada).

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