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Salflex Oral

Generic Name: SALSALATE - ORAL
Pronounced: (SAL-suh-late)

Salflex Oral Warning

Nonsteroidal anti-inflammatory drugs (including salsalate) may rarely increase the risk for a heart attack or stroke. This effect does not apply to low-dose aspirin. (See Drug Interactions section.) The risk may be greater in people with heart disease or increased risk for heart disease (e.g., due to high blood pressure, diabetes), or with longer use. This drug should not be taken right before or after heart bypass surgery (CABG). Also, this drug may infrequently cause serious (rarely fatal) bleeding from the stomach or intestines. This bleeding can occur without warning symptoms at any time during treatment.



Stop taking this medication and seek immediate medical attention if you notice any of the following rare but very serious side effects: chest pain, severe dizziness, weakness on one side of the body, sudden vision changes, slurred speech, black stools, persistent stomach/abdominal pain, vomit that looks like coffee grounds. (See also Precautions section.)

Talk with your doctor or pharmacist about the risks and benefits of treatment with this medication.

Salflex Oral Side Effects

Upset stomach, dizziness, or nausea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • stomach pain
  • heartburn
  • swelling of ankles/feet/hands
  • sudden/unexplained weight gain
  • hearing changes (e.g., ringing in the ears, decreased hearing)


Stop taking salsalate and tell your doctor immediately if any of these rare but very serious side effects occur:

  • fast/pounding heartbeat
  • change in the amount of urine
  • easy bruising/bleeding
  • signs of infection (e.g., fever, persistent sore throat)


This drug may rarely cause serious, possibly fatal liver disease. If you notice any of the following rare but very serious side effects, stop taking salsalate and consult your doctor or pharmacist immediately:

  • dark urine
  • yellowing eyes/skin
  • unusual/extreme tiredness
  • severe stomach/abdominal pain
  • persistent nausea/vomiting


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching
  • swelling
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

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