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Salflex Oral

  • dark urine
  • yellowing eyes/skin
  • unusual/extreme tiredness
  • severe stomach/abdominal pain
  • persistent nausea/vomiting


A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Salflex Oral Precautions

Before taking salsalate, tell your doctor or pharmacist if you are allergic to it; or to aspirin or other NSAIDs (e.g., ibuprofen, naproxen, celecoxib); or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • aspirin-sensitive asthma (a history of worsening breathing with runny/stuffy nose after taking aspirin or other NSAIDs)
  • severe kidney disease


Before using this medication, tell your doctor or pharmacist your medical history, especially of:

  • kidney disease
  • liver disease
  • poorly controlled diabetes
  • stomach/intestine/esophagus problems (e.g., bleeding, ulcers, recurring heartburn)
  • heart disease (e.g., congestive heart failure, history of heart attack)
  • high blood pressure
  • stroke
  • swelling of the ankles/feet/hands
  • a severe loss of body water (dehydration)
  • blood disorders (e.g., anemia)
  • bleeding/clotting problems
  • asthma
  • growths in the nose (nasal polyps)
  • certain genetic conditions (G-6-PD deficiency, pyruvate kinase deficiency)


Before having surgery, tell your doctor or dentist that you are using this medication.

This drug may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Limit alcoholic beverages.

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