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Anafranil Oral

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • mental/mood changes (e.g., confusion, depression, hallucinations, memory problems)
  • enlarged/painful breasts
  • unwanted breast milk production
  • irregular/painful menstrual periods
  • muscle stiffness/twitching
  • feelings of restlessness
  • ringing in the ears
  • sexual problems (e.g., decreased sexual ability, changes in desire)
  • shakiness (tremors)
  • numbness/tingling of the hands/feet
  • trouble urinating
  • severe vomiting


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • easy bruising/bleeding
  • signs of infection (e.g., fever, persistent sore throat)
  • unusual/uncontrolled movements (especially of the tongue/face/lips)
  • severe stomach/abdominal pain
  • dark urine
  • yellowing of eyes/skin


Seek immediate medical attention if any of these rare but very serious side effects occur:

  • black stools
  • chest pain
  • fainting
  • high fever
  • slow/fast/irregular heartbeat
  • seizures
  • vomit that looks like coffee grounds


A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Anafranil Oral Precautions

Before taking clomipramine, tell your doctor or pharmacist if you are allergic to it; or to other tricyclic antidepressants (e.g., imipramine, nortriptyline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have had:

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