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Zipan-25 Inj

In Depth

Generic Name: PROMETHAZINE - INJECTION
Pronounced: (pro-METH-uh-zeen)

Zipan-25 Inj Warning

Promethazine should not be used in children younger than 2 years since it might cause slow/shallow breathing (respiratory depression), which in some cases could be fatal. This problem has occurred even with normal doses in this age group.

Use this drug with caution in children older than 2 years. The lowest effective dosage should be used, and other drugs that affect breathing should be avoided. Seek immediate medical attention in the unlikely event that slow/shallow breathing occurs.

In children, use drugs for nausea only in cases of prolonged vomiting with a known cause. Avoid use of promethazine in children with liver disease (including possible Reye's syndrome).

Zipan-25 Inj Side Effects

Drowsiness, dizziness, constipation, blurred vision, or dry mouth may occur. If any of these effects persist or worsen, notify your doctor.

Some people, especially children, may experience excitability rather than drowsiness.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

This medication can cause severe tissue damage, possibly requiring surgery. Tell your doctor/nurse immediately if you experience burning, pain, redness, swelling, or numbness at or near the injection site.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • lack of coordination
  • severe dizziness
  • fainting
  • slow/fast heartbeat
  • muscle stiffness
  • involuntary muscle movements
  • muscle spasms (e.g., rolling eyes, twisting neck/back)
  • restlessness
  • decreased/painful urination


Seek immediate medical attention if any of these unlikely but very serious side effects occur:

  • slow/shallow breathing
  • difficulty waking up
  • hot/dry skin


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • signs of serious infection (e.g., persistent sore throat, fever)
  • unusual bleeding/ bruising
  • severe stomach/abdominal pain
  • yellowing of eyes/skin
  • dark urine
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