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Wellbutrin SR Oral

  • fainting
  • chest pain
  • fast heartbeat
  • severe headache
  • uncontrolled movements (tremor)
  • unusual weight loss or gain
  • ringing in the ears
  • mental/mood changes (e.g., agitation, anxiety, hallucinations, nervousness, confusion, restlessness)


Tell your doctor immediately if any of these rare but very serious side effects occur:

  • muscle pain/tenderness/weakness
  • change in the amount of urine


This drug may rarely cause seizures. Seek immediate medical attention if you have a seizure while taking bupropion. If you have a seizure while taking bupropion, you should not take this drug again.

A severe allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a severe allergic reaction include:

  • rash
  • itching/swelling (especially of the face/tongue/throat)
  • severe dizziness
  • trouble breathing


An empty tablet shell may appear in your stool. This is harmless.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Wellbutrin SR Oral Precautions

See also How to Use and Warning Sections

Before taking bupropion, tell your doctor or pharmacist if you are allergic to it or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

  • seizures
  • eating disorders (e.g., bulimia, anorexia nervosa)


This medication should not be used if you are suddenly stopping regular use of sedatives (e.g., benzodiazepines such as lorazepam) or alcohol, which can cause a higher risk of seizures.

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

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