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Pediazole Oral

Generic Name: ERYTHROMYCIN/SULFISOXAZOLE SUSPENSION - ORAL
Pronounced: (eh-rith-row-MY-sin/sull-fih-SOX-uh-zole)

Pediazole Oral Side Effects

Nausea, vomiting, diarrhea, stomach pain/cramping, and loss of appetite may occur. Taking this medication with food may lessen these symptoms. Headache and dizziness may also occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • mouth sores
  • sun sensitivity (sunburn)
  • hearing problems (e.g., hearing loss)
  • joint pain/aches
  • new lump/growth in the neck (goiter)
  • change in the amount of urine
  • mental/mood changes (e.g., confusion)
  • numbness or tingling of the hands/feet
  • muscle weakness


This medication may rarely cause serious (possibly fatal) allergic reactions and other side effects such as a severe peeling skin rash (e.g., Stevens-Johnson syndrome), blood disorders (e.g., agranulocytosis, aplastic anemia), liver damage, lung injury, or heart problems. Seek immediate medical attention if you notice any of the following symptoms:

  • severe dizziness
  • fainting
  • fast/irregular heartbeat
  • skin rash/blisters
  • itching/swelling (especially of the face/tongue/throat)
  • persistent sore throat/fever
  • paleness
  • persistent cough
  • trouble breathing
  • easy bleeding/bruising
  • yellowing eyes/skin
  • persistent nausea/vomiting
  • seizures
  • stomach/abdominal pain
  • unusual tiredness
  • dark urine


This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to resistant bacteria. This condition may occur during treatment or weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop:

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