Esclim TD

In Depth

Tell your doctor immediately if any of these unlikely but serious side effects occur:

mental/mood changes (e.g., severe depression, memory loss)
vision changes (e.g., change in contact lens fit, loss of vision)
swelling of hands or feet
stomach/abdominal/pelvic pain
vomiting
breast lumps
unusual vaginal bleeding (e.g., spotting, breakthrough bleeding, prolonged/recurrent bleeding)
unusual vaginal discharge/itching/odor
yellowing of the eyes or skin

Seek immediate medical attention if any of these unlikely but serious side effects occur:

calf pain/swelling
sudden severe headache
chest pain
trouble breathing
weakness on one side of the body
slurred speech

A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include:

rash
itching/swelling (especially of the face/tongue/throat)
severe dizziness
trouble breathing

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Esclim TD Precautions

Before using estradiol, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have:

undiagnosed abnormal vaginal bleeding
certain cancers (e.g., breast cancer, especially non-metastatic type)
current/history of blood clots
history of stroke or heart attack
liver disease

Before using this medication, tell your doctor or pharmacist your medical history, especially of:

family medical history (especially breast lumps and cancer)
asthma
diabetes
seizures
migraine headaches
heart disease (e.g., high blood pressure, congestive heart failure)
kidney disease
low thyroid hormone (hypothyroidism)
a certain hormone problem (hypoparathyroidism)
abnormal calcium level in the blood
depression
high blood pressure during pregnancy (toxemia)
yellowing of eyes and skin (cholestatic jaundice) during pregnancy or with past estrogen use
womb problems (e.g., uterine fibroids, endometriosis)
cholesterol or lipid problems
gallbladder disease
excessive weight gain
certain blood disorder (porphyria)