Amitriptyline W/Perphenazine Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (am-eh-TRIP-teh-leen/per-FEN-uh-zeen)
Amitriptyline W/Perphenazine Oral Uses
This medication is used to treat depression occurring with anxiety/agitation or with certain mental/mood disorders (e.g., schizophrenia). This medication is a combination of a tricyclic antidepressant (amitriptyline) and an antipsychotic medication (perphenazine). Together, they restore the balance of certain natural chemicals in the brain (neurotransmitters such as dopamine, norepinephrine, and serotonin). This medication helps you to have a better mood and sense of well-being, think more clearly, and feel less nervous, so that you can take part in everyday life.
How To Use Amitriptyline W/Perphenazine Oral
Read the Medication Guide provided by your pharmacist before you start using this medication and each time you get a refill. If you have any questions, consult your doctor or pharmacist.
Take this medication by mouth as directed by your doctor. When you begin treatment, frequent visits to your doctor may be needed to find the best dose for you. Keep all medical/lab appointments.
Dosage is based on your medical condition and response to treatment. Your doctor may direct you to take a low dose at first, gradually increasing the dose to lower the chance of side effects such as muscle spasms. Follow your doctor's directions carefully. The manufacturer recommends that you do not take more than 16 milligrams of perphenazine or 200 milligrams of amitriptyline per day.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same times each day. Do not stop taking this medication without consulting your doctor. Your condition may become worse when the drug is suddenly stopped. Muscle aches, headaches, and worsening anxiety may also occur. Your dose may need to be gradually decreased.
Although you may notice some medication effects soon after starting, it may take as much as 4 to 6 weeks of regular use to see the full benefit. Tell your doctor if your condition persists or worsens after this period (e.g., your feelings of sadness get worse, or you have thoughts of suicide).
