Zofran IV
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (on-DANS-eh-tron)
Zofran IV Uses
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer chemotherapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.
How To Use Zofran IV
To prevent nausea from chemotherapy, ondansetron may be given as a single dose or 3 smaller doses. It is mixed in a solution and given by injection into a vein as directed by your doctor, usually over 15 minutes. This drug is usually started 30 minutes before your chemotherapy treatment begins. Do not give this medication any faster than recommended because this may increase the chance of serious side effects such as blurred vision or slowed/irregular heartbeat. Depending on the type of chemotherapy treatment you are receiving, a smaller first dose may be used, and a second and third dose may be given 4 and 8 hours after your first dose. You may also be switched to a medication you can take by mouth, or a low dose of ondansetron may be given continuously through an IV for up to 24 hours.
Your doctor may direct you to continue this medication for 1 or 2 days after your chemotherapy treatment. If you are using this medication on a prescribed schedule, use it regularly to get the most benefit from it. To help you remember, use it at the same times each day. Use this medication exactly as directed. Do not use more medication or use it more often than prescribed. Ask your doctor or pharmacist if you have questions.
To prevent or treat nausea after surgery, a single dose of ondansetron may be given undiluted into a muscle or vein (IV) shortly before the start of surgery, during surgery, or after surgery. It is best to give IV ondansetron over 2 to 5 minutes to decrease side effects such as dizziness. When given through an IV, ondansetron should not be given over less than 30 seconds.
If you are giving this medication to yourself at home, learn all preparation and usage instructions from your health care professional. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid. Learn how to store and discard medical supplies safely.
Dosage is based on your weight, medical condition, type of treatment, and response to therapy.
Tell your doctor if your condition does not improve or if it worsens.
