Zofran IV
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (on-DANS-eh-tron)
Zofran IV Uses
This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer chemotherapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.
How To Use Zofran IV
Before using, check this product visually for discoloration. Ondansetron injection should be clear and colorless. If discoloration is present, do not use the liquid. When the vial is stored upright after first use, clumps may occasionally form on the top of the vial. Check the vial and the vial top carefully for particles. If particles are present, shake the vial to re-dissolve the particles. If any particles remain after the vial is shaken, do not use the liquid. Follow all instructions for proper mixing with the correct IV fluids. If you have any questions about the use of this medication, consult your pharmacist.
To prevent nausea from chemotherapy, ondansetron may be given as a single dose or 3 smaller doses. It is mixed in a solution and given into a vein (IV) by a health care professional, usually over 15 minutes or as directed by your doctor. This drug is usually started 30 minutes before your chemotherapy treatment begins. Do not give this medication any faster than recommended because this may increase the chance of serious side effects such as blurred vision or slowed/irregular heartbeat. Depending on the type of chemotherapy treatment you are receiving, a smaller first dose may be used, and a second and third dose may be given 4 and 8 hours after your first dose. You may also be switched to a medication you can take by mouth, or a low dose of ondansetron may be given continuously through an IV for up to 24 hours.
Your doctor may direct you to continue this medication for 1 or 2 days after your chemotherapy treatment. If you are using this medication on a prescribed schedule, use it regularly to get the most benefit from it. To help you remember, use it at the same times each day. Use this medication exactly as directed. Do not use more medication or use it more often than prescribed. Ask your doctor or pharmacist if you have questions.
