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Tobramycin Sulfate Inj

In Depth

Generic Name: TOBRAMYCIN - INJECTION
Pronounced: (toe-bruh-MY-sin)

Tobramycin Sulfate Inj Warning

This medication can cause serious kidney problems and nerve damage, resulting in permanent hearing loss and balance problems. Before starting tobramycin, tell your doctor if you already have kidney or hearing problems. The risk is increased if you already have kidney disease, are receiving high doses of this medication, are on prolonged treatment, are older, or if you have a severe loss of body water (become dehydrated).

Tell your doctor immediately if you notice ringing/roaring in the ears, hearing loss, unusual decrease in the amount of urine, dizziness, numbness, skin tingling, muscle twitching, or seizure. This medication may be stopped if you develop kidney problems or hearing problems.

Your doctor will monitor your progress to reduce the risk of these side effects and may test your hearing, kidney, urine, and tobramycin blood level.

If possible, you should avoid using any other medications that have kidney/nerve side effects while using tobramycin (e.g., cidofovir, cisplatin, high-dose aspirin, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen or naproxen, kanamycin, gentamicin, neomycin, cyclosporine, polymyxin B, colistin, paromomycin, streptomycin, amikacin, vancomycin, viomycin, among others).

Strong "water pills"/diuretics (e.g., furosemide, ethacrynic acid) should also be avoided if possible.

Tobramycin Sulfate Inj Side Effects

See also Warning section.

Nausea, vomiting, stomach upset, or loss of appetite may occur. Pain/irritation/redness may occur at the injection site. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur:

  • persistent diarrhea even after stopping this medication
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