Vytorin 10-20 Oral

Vytorin 10-20 Oral Interactions

See also How To Use section above.

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious, possibly fatal interactions may occur:

• certain azole antifungals (e.g., itraconazole, ketoconazole)
• delavirdine
• HIV protease inhibitors (e.g., ritonavir, amprenavir, lopinavir)
• certain macrolide antibiotics (e.g., erythromycin, clarithromycin, troleandomycin)
• nefazodone
• telithromycin

If you are currently using any of these medications, tell your doctor or pharmacist before starting ezetimibe/simvastatin.

Use caution if you are taking the following drugs in combination with this product because serious side effects such as muscle injury (myopathy) could sometimes occur:

• fibrates (e.g., gemfibrozil, fenofibrate)
• high-dose niacin (1 gram or more per day)

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• "blood thinners" (e.g., warfarin)
• danazol
• daptomycin
• digoxin
• other drugs which affect certain liver enzymes (CYP 3A4 substrates, inhibitors, and inducers such as amiodarone, cyclosporine, diltiazem, verapamil, rifampin, St. John's wort, carbamazepine)

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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