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Prazosin Oral

Generic Name: PRAZOSIN - ORAL
Pronounced: (PRAY-zoh-sin)

Prazosin Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • beta blockers (e.g., atenolol, metoprolol, propranolol)
  • verapamil
  • drugs for sexual function problems (e.g., sildenafil, tadalafil, vardenafil)


If you are taking sildenafil at doses greater than 25 milligrams, you can decrease your risk of fainting by taking sildenafil at least four hours apart from your prazosin. Consult your doctor or pharmacist if you have any questions.

Tell your doctor or pharmacist if you also take drugs that can cause drowsiness, lower your blood pressure, or make it difficult for you to urinate such as:

  • certain antihistamines (e.g., diphenhydramine)
  • anti-anxiety drugs (e.g., diazepam)
  • anti-seizure drugs (e.g., carbamazepine)
  • medicine for sleep (e.g., sedatives)
  • muscle relaxants (e.g., carisoprodol)
  • narcotic pain relievers (e.g., codeine)
  • psychiatric medicines (e.g., phenothiazines such as chlorpromazine or tricyclic antidepressants such as amitriptyline)
  • tranquilizers


Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or cause a fast heartbeat (e.g., pseudoephedrine, phenylephrine, chlorpheniramine, diphenhydramine, clemastine, ibuprofen, naproxen). Ask your pharmacist about the safe use of those products.

This product can affect the results of certain lab tests (pheochromocytoma screening test). Make sure laboratory personnel and your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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