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Ak-Zol Oral

Generic Name: ACETAZOLAMIDE - ORAL
Pronounced: (a-SEET-a-ZOLE-a-mide)

Ak-Zol Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • cisapride
  • methenamine


If you are currently using either of these medications listed above, tell your doctor or pharmacist before starting acetazolamide.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially:

  • anticonvulsants (e.g., phenytoin, primidone, phenobarbital)
  • other diuretics similar to this medication (carbonic anhydrase inhibitors such as brinzolamide, dorzolamide)
  • cyclosporine
  • digoxin
  • drugs for diabetes (e.g., glyburide, insulin)
  • drugs that cause loss of potassium (e.g., diuretics such as furosemide, corticosteroids such as prednisone, amphotericin B)
  • folic acid antagonists (e.g., methotrexate, trimethoprim)
  • lithium
  • memantine
  • procainamide
  • quinidine
  • salicylates (e.g., aspirin, bismuth subsalicylate)
  • sodium bicarbonate
  • stimulants (e.g., amphetamines, ephedrine)
  • topiramate
  • tricyclic antidepressants (e.g., amitriptyline)


Check all prescription and nonprescription labels carefully since they may contain medications (e.g., anti-diarrhea drugs, pain relievers/fever reducers) similar to aspirin, which can cause serious side effects when taken with acetazolamide. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day), should be continued. Consult your doctor or pharmacist for more details.

This medication may interfere with certain laboratory tests, possibly causing false test results. Make sure laboratory personnel and your doctor know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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