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Tacrine Oral

Generic Name: TACRINE - ORAL
Pronounced: (TACK-reen)

Tacrine Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • anticholinergic medications (e.g., benztropine, diphenhydramine)
  • aspirin (high doses, such as those used for arthritis)
  • cholinergic drugs (e.g., bethanechol)
  • drugs affecting liver enzymes that remove tacrine from your body (e.g., cimetidine, fluvoxamine)
  • nonsteroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, naproxen)
  • succinylcholine
  • theophylline


Smoking tobacco decreases blood levels of this medication (hepatic enzyme induction). Tell your doctor if you smoke or if you have recently stopped smoking.

Check all prescription and nonprescription medicine labels carefully since many medications contain pain relievers/fever reducers (NSAIDs such as aspirin, ibuprofen, or naproxen) which, if taken together with tacrine, may increase your risk for stomach/intestinal bleeding. Low-dose aspirin, as prescribed by your doctor for specific medical reasons such as heart attack or stroke prevention (usually at dosages of 81-325 milligrams per day), should be continued. Consult your doctor or pharmacist for more details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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