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Diltiazem HCl Oral

Generic Name: DILTIAZEM TABLET - ORAL
Pronounced: (dill-TIE-uh-zem)

Diltiazem HCl Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • disopyramide
  • ranolazine


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting diltiazem.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • amiodarone
  • aspirin
  • beta blockers (e.g., metoprolol, propranolol, timolol)
  • cilostazol
  • digoxin
  • inhaled anesthetics used during surgery (e.g., halothane)
  • drugs that affect how your body gets rid of diltiazem (cimetidine, rifamycins including rifabutin and rifampin, St. John's wort)


Diltiazem may also affect how your body gets rid of many drugs (e.g., buspirone, cyclosporine, sirolimus, tacrolimus, atazanavir, erythromycin, quinidine, statins including lovastatin, certain anti-seizure drugs including carbamazepine, certain benzodiazepines including triazolam and midazolam).

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or heart rate (e.g., pseudoephedrine, phenylephrine, chlorpheniramine, diphenhydramine, clemastine, ibuprofen, naproxen). Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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