Ibuprofen-Oxycodone Oral

Ibuprofen-Oxycodone Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

• cidofovir
• ketorolac
• naltrexone
• MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine)

Avoid using MAO inhibitors within 14 days before or after using this medication.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting this medication.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• anti-platelet drugs (e.g., cilostazol, clopidogrel)
• oral bisphosphonates (e.g., alendronate)
• "blood thinners" (e.g., enoxaparin, heparin, warfarin)
• corticosteroids (e.g., prednisone)
• cyclosporine
• desmopressin
• anti-seizure drugs (e.g., carbamazepine, phenobarbital)
• anticholinergic medications (e.g., atropine, scopolamine)
• drugs that lower blood pressure (e.g., diuretics such as hydrochlorothiazide and furosemide, ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan, and beta-blockers such as metoprolol)
• other medications for pain (e.g., butorphanol, buprenorphine, pentazocine, tramadol)
• SSRI antidepressants (e.g., fluoxetine, sertraline)
• muscle relaxants (e.g., carisoprodol, methocarbamol)
• pyridostigmine
• sodium oxybate
• lithium
• methotrexate
• pemetrexed
• probenecid

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as:

• antihistamines that cause drowsiness (e.g., diphenhydramine)
• anti-anxiety drugs (e.g., diazepam)
• medicine for sleep (e.g., zolpidem)
• psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline)
• tranquilizers

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