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Vaseretic Oral

Generic Name: ENALAPRIL/HYDROCHLOROTHIAZIDE - ORAL
Pronounced: (e-NAL-a-pril/HYE-droe-KLOR-oh-THYE-a-zide)

Vaseretic Oral Interactions

See also Precautions section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medication because very serious interactions may occur:

  • dofetilide


Before using enalapril/hydrochlorothiazide, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • cisapride
  • lithium
  • drugs that may affect your potassium level (including drospirenone, potassium-sparing "water pills"/diuretics such as spironolactone, corticosteroids such as prednisone)
  • gold injections


A very serious reaction may occur if you are getting injections for bee/wasp sting allergy (desensitization) and are also taking enalapril/hydrochlorothiazide. Make sure all your doctors know which medicines you are using.

Cholestyramine and colestipol can decrease the absorption of hydrochlorothiazide. If you are taking either of these drugs, separate them from hydrochlorothiazide by at least 4 hours.

Check the labels on all your medicines (such as cough-and-cold products, diet aids, nonsteroidal anti-inflammatory drugs-NSAIDs such as ibuprofen for pain/fever reduction) because they may contain ingredients that could increase your blood pressure or heart rate. Ask your pharmacist about using those products safely.

Some nonprescription medicines may also contain aspirin, which may decrease the effect of the enalapril in this product. If your doctor has directed you to take low-dose aspirin for heart attack or stroke prevention (usually at dosages of 81-325 milligrams a day), you should continue taking it unless your doctor instructs you otherwise. Ask your doctor or pharmacist for more details.

This medication may interfere with certain laboratory tests (including parathyroid, protein-bound iodide, tyramine, and phentolamine tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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