Revatio Oral

Revatio Oral Interactions

See also How to Use section.

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur:

• nitrates (e.g., nitroglycerin, isosorbide)
• medications for erectile dysfunction (e.g., PDE5 inhibitors such as tadalafil)
• certain recreational drugs ("poppers") containing amyl/butyl nitrite

If you are currently using any of these medications, tell your doctor or pharmacist before starting sildenafil.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription products you may use, especially of:

• alpha blocker medication (e.g., doxazosin, prazosin, terazosin)
• bosentan
• high blood pressure medicines (e.g., beta blockers such as propranolol/atenolol, calcium channel blockers such as amlodipine)
• nitroprusside (or any "nitric oxide donor" drugs)
• drugs affecting liver enzymes that remove sildenafil from your body (e.g., anticonvulsants such as carbamazepine/phenobarbital/phenytoin, azole antifungals such as ketoconazole/itraconazole, macrolide antibiotics such as erythromycin, rifamycins such as rifampin/rifabutin, protease inhibitors such as ritonavir/saquinavir, delavirdine)
• warfarin

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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Precautions and Side Effects