Ranolazine Oral
In Depth
- Uses and How to Use
- Dosage and Storage
- Precautions and Side Effects
- Drug Interactions
- Drug Images
Pronounced: (ra-NOE-la-zeen)
Ranolazine Oral Interactions
Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.
This drug should not be used with the following medications because very serious interactions may occur:
- drugs that strongly affect the removal of ranolazine from your body (including azole antifungals such as itraconazole/ketoconazole, macrolide antibiotics such as clarithromycin, HIV protease inhibitors such as ritonavir, rifamycins such as rifampin, St. John's wort, drugs used to treat seizures such as carbamazepine/phenytoin)
If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting ranolazine.
Many drugs besides ranolazine may affect the heart rhythm (QT prolongation), including amiodarone, pimozide, dofetilide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using ranolazine, report all medications you are currently using to your doctor or pharmacist.
Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:
- other drugs that affect the removal of ranolazine from your body (e.g., aprepitant, cyclosporine, diltiazem, erythromycin, fluconazole, verapamil)
Ranolazine can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include digoxin, trazodone, tricyclic antidepressants (such as amitriptyline, imipramine), certain antipsychotics (such as clozapine, haloperidol, risperidone), among others.
This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.
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