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Rasagiline Oral

Generic Name: RASAGILINE - ORAL
Pronounced: (ra-SA-ji-leen)

Rasagiline Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious (possibly fatal) interactions may occur:

  • antidepressants (e.g., TCAs such as amitriptyline/protriptyline, mirtazapine, nefazodone, SSRIs such as fluoxetine/paroxetine/sertraline, venlafaxine)
  • other MAO inhibitors (furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine)
  • appetite suppressants (e.g., diethylpropion, sibutramine)
  • drugs for attention deficit disorder (e.g., atomoxetine, methylphenidate)
  • certain antihistamines (azatadine, carbetapentane, chlorpheniramine)
  • bronchodilators (e.g., albuterol, salmeterol)
  • bupropion
  • buspirone
  • cyclobenzaprine
  • dextromethorphan
  • certain drugs for glaucoma (e.g., apraclonidine, brimonidine)
  • certain herbal products (e.g., ephedra/ma huang, St. John's wort)
  • certain drugs for high blood pressure (e.g., guanethidine, methyldopa)
  • nasal decongestants (e.g., phenylephrine, pseudoephedrine)
  • certain narcotic medications (e.g., meperidine, methadone, propoxyphene)
  • street drugs (e.g., MDMA/"ecstasy", LSD, mescaline)
  • stimulants (e.g., amphetamines, ephedrine, epinephrine, phenylalanine)
  • "triptan" migraine drugs (e.g., sumatriptan, rizatriptan)
  • tramadol


If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting rasagiline. Do not take these medications within 2 weeks before, during, or after treatment with rasagiline. If you have been taking fluoxetine, wait at least 5 weeks before starting rasagiline. Discuss with your doctor how much time to wait between starting or stopping any of these drugs and taking rasagiline.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

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