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Tolmetin Oral

Generic Name: TOLMETIN SODIUM - ORAL
Pronounced: (tole-MET-in SO-dee-um)

Tolmetin Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

  • cidofovir
  • ketorolac


If you are currently using either of the medications listed above, tell your doctor or pharmacist before starting tolmetin.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • anti-platelet drugs (e.g., cilostazol, clopidogrel)
  • bisphosphonates taken by mouth (e.g., alendronate)
  • "blood thinners" (e.g., enoxaparin, heparin, warfarin)
  • corticosteroids (e.g., prednisone)
  • cyclosporine
  • desmopressin
  • drugs for high blood pressure (including ACE inhibitors such as captopril, angiotensin II receptor antagonists such as losartan, and beta blockers such as metoprolol)
  • lithium
  • methotrexate
  • pemetrexed
  • probenecid
  • SSRI antidepressants (e.g., fluoxetine, sertraline)
  • tenofovir
  • "water pills" (diuretics such as furosemide, hydrochlorothiazide, triamterene)


Check all prescription and nonprescription medicine labels carefully for other pain/fever drugs (NSAIDs such as aspirin, celecoxib, ibuprofen). These drugs are similar to this medication, so taking one of these drugs while also taking this medication may increase your risk of side effects. However, if your doctor has prescribed low doses of aspirin to prevent heart attack or stroke (usually at dosages of 81-325 milligrams a day), you should continue to take the aspirin. Daily use of NSAIDs (e.g., ibuprofen) may decrease aspirin's ability to prevent heart attack/stroke. Consult your doctor or pharmacist for more details and to discuss other possible treatments (e.g., acetaminophen) for your pain/fever.

This product can affect the results of certain lab tests (e.g., protein in urine), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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