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Zemplar Oral

Generic Name: PARICALCITOL - ORAL
Pronounced: (pear-ih-KAL-sit-ole)

Zemplar Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because a very serious interaction may occur:

  • other vitamin D products (e.g., ergocalciferol)


If you are currently using any of the medications listed above, tell your doctor or pharmacist before starting paricalcitol.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially:

  • corticosteroids (e.g., prednisone)
  • digoxin
  • drugs affecting liver enzymes that remove paricalcitol from your body (such as azole antifungals including ketoconazole/itraconazole, macrolide antibiotics including clarithromycin, nefazodone, HIV protease inhibitors including indinavir/ritonavir)
  • phosphate binders
  • thiazide diuretics (e.g., hydrochlorothiazide)


Check the labels on all your prescription and nonprescription/herbal products (e.g., antacids, vitamins) because they may contain calcium, phosphate, and vitamin D. Ask your pharmacist about using those products safely.

Certain medications can decrease the absorption of vitamin D (bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat). Therefore, separate your doses of these medications as far as possible from your doses of vitamin D (at least 2 hours apart, longer if possible). It may be easiest to take vitamin D at bedtime if you are also taking these other medications. Ask your doctor or pharmacist about how long you should wait between doses and for help finding a dosing schedule that will work with all your medications.

This medication may interfere with certain laboratory tests (including cholesterol tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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