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Dilaudid Inj

Generic Name: HYDROMORPHONE - INJECTION
Pronounced: (hye-droe-MOR-fone)

Dilaudid Inj Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur:

  • mixed opioid agonists/antagonists (e.g., buprenorphine, butorphanol, nalbuphine, pentazocine)
  • naltrexone


Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before, during, or after treatment with this medication. In some cases, a serious (possibly fatal) drug interaction may occur.

If you are currently using any of these medications, tell your doctor or pharmacist before starting hydromorphone.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • amphetamines
  • water pills (diuretics such as furosemide)
  • drugs affecting liver enzymes that remove hydromorphone from your body (e.g., cimetidine, rifamycins including rifampin)


Tell your doctor or pharmacist if you also take drugs that may cause drowsiness, slow your breathing, or lower your blood pressure such as:

  • antihistamines that cause drowsiness (e.g., diphenhydramine)
  • anti-anxiety drugs (e.g., diazepam)
  • anti-seizure drugs (e.g., carbamazepine)
  • medicine for sleep or anxiety (e.g., sedatives, hypnotics)
  • muscle relaxants
  • other narcotic pain relievers (e.g., codeine)
  • psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline)
  • tranquilizers


Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely.

This product can affect the results of certain lab tests (e.g., amylase, lipase). Make sure laboratory personnel and all your doctors know you use this drug.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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