Amprenavir Oral

In Depth

Generic Name: AMPRENAVIR SOLUTION - ORAL
Pronounced: (am-PREN-a-vir)

Amprenavir Oral Interactions

See also Warning and How to Use sections.

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

etravirine
metronidazole
disulfiram
ritonavir solution
amiodarone
bepridil
delavirdine
quinidine
tricyclic antidepressants (e.g., amitriptyline, desipramine, imipramine)
cisapride
pimozide
dihydroergotamine
ergonovine
ergotamine
methylergonovine
St Johns wort
midazolam
triazolam
simvastatin
lovastatin
rifampin
ranolazine
artemether/lumefantrine

Avoid using hormonal birth control (e.g., pills, patch, ring) while taking this medication. Using hormonal birth control while also taking this medication can make both drugs less effective. Consult your doctor or pharmacist for more details and for information about other birth control methods. To reduce the risk of spreading HIV to others, always use effective barrier protection during all sexual activity. (See also Notes section.)

If amprenavir is taken with ritonavir, the following medications should also not be used:

flecainide
propafenone

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

garlic capsules
sildenafil
tadalafil
vardenafil
trazodone
ketoconazole
itraconazole
saquinavir
lopinavir/ritonavir
ritonavir capsules
indinavir
nelfinavir
didanosine (dispersible tablets/solution)
nevirapine
efavirenz
carbamazepine
phenobarbital
phenytoin
rifabutin
fluticasone
atorvastatin
certain calcium channel blockers (e.g., nifedipine, felodipine, nicardipine)
warfarin
ranitidine
dexamethasone
certain drugs that weaken the immune system (cyclosporine, tacrolimus, sirolimus)
temsirolimus
alprazolam
diazepam
flurazepam
clonazepam
clorazepate
estazolam
methadone

If any of these medications are taken with amprenavir, your doctor may change your dose of amprenavir or the other drug(s), or your doctor may monitor you specially. Consult your doctor or pharmacist for more details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.