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Risperidone Oral

Generic Name: RISPERIDONE - ORAL
Pronounced: (riss-PAIR-ih-doan)

Risperidone Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medication because a very serious interaction may occur:

  • sibutramine


If you are currently using the medication listed above, tell your doctor or pharmacist before starting risperidone.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • antidepressants (e.g., fluoxetine, paroxetine)
  • high blood pressure medicine (e.g., beta-blockers such as propranolol, alpha-blockers such as doxazosin or prazosin)
  • medications for Parkinson's disease (e.g., levodopa)


Many drugs besides risperidone may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), thioridazine, sparfloxacin, among others. Therefore, before using risperidone, report all medications you are currently using to your doctor or pharmacist.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: medicine for sleep (e.g., sedatives), tranquilizers, anti-anxiety drugs (e.g., diazepam), narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., phenothiazines such as chlorpromazine, or tricyclics such as amitriptyline), anti-seizure drugs (e.g., carbamazepine), muscle relaxants, antihistamines that cause drowsiness (e.g., diphenhydramine).

Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of those products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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