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Your Prescription Drug Destination
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Baclofen IT

Generic Name: BACLOFEN - INJECTION
Pronounced: (BACK-low-fen)

Baclofen IT Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use.



Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as:

  • certain antihistamines (e.g., diphenhydramine)
  • anti-seizure drugs (e.g., carbamazepine)
  • medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem)
  • narcotic pain relievers (e.g., codeine)
  • psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone)


Check the labels on all your medicines (e.g., cough-and-cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about using those products safely.

Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with baclofen such as phenothiazines (e.g., thioridazine), tricyclic antidepressants (e.g., amitriptyline), isoniazid (INH), or theophylline, among others. Consult your doctor or pharmacist for details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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Precautions and Side Effects



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