Ephedrine-Guaifenesin Oral

Ephedrine-Guaifenesin Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

• MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine, rasagiline)

Avoid taking MAO inhibitors within 2 weeks before, during, and after treatment with guaifenesin/ephedrine. In some cases a serious, possibly fatal drug interaction may occur.

If you are currently using any of these medications, tell your doctor or pharmacist before starting this product.

Before using guaifenesin/ephedrine, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

• other drugs for asthma (e.g., albuterol, theophylline)
• decongestants (taken by mouth or sprayed into the nose)
• products containing caffeine
• tricyclic antidepressants (e.g., nortriptyline, amitriptyline)
• digoxin
• inhaled anesthetics (e.g., halothane, isoflurane)
• mecamylamine

Ephedrine may decrease the effectiveness of some blood pressure medications (e.g., beta blockers, calcium channel blockers, reserpine, guanethidine, methyldopa), alpha blockers (e.g., prazosin, terazosin), oxytocin, atropine, "water pills"/diuretics (e.g., furosemide, hydrochlorothiazide).

Ephedrine may also worsen the serious side effects of some medications for migraine headaches (e.g., sumatriptan, naratriptan, zolmitriptan, ergotamine, caffeine). Consult your pharmacist or doctor for more details.

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure (e.g., pseudoephedrine, phenylephrine). Ask your pharmacist about the safe use of those products before using them.

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Precautions and Side Effects