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Midodrine Oral

Generic Name: MIDODRINE - ORAL
Pronounced: (MY-doh-dreen)

Midodrine Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) within 2 weeks before or after treatment with this medication. In some cases, a serious (possibly fatal) drug interaction may occur.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • adrenaline-like drugs (e.g., ephedrine, phenylephrine, pseudoephedrine)
  • alpha blockers (e.g., doxazosin, prazosin, terazosin)
  • beta-blockers (e.g., atenolol, metoprolol)
  • digoxin
  • ergot alkaloids (e.g., dihydroergotamine, ergotamine)
  • drugs to control high blood pressure
  • psychiatric medications (especially certain antidepressants and antipsychotic drugs)


If you are also taking fludrocortisone for low blood pressure when standing, be sure to regularly monitor your blood pressure, especially when you are lying down. You will be at a greater risk for developing supine hypertension while using these 2 drugs together. (See also Side Effects section.)

Check the labels on all your medicines (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your blood pressure. Ask your pharmacist about using those products safely.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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