Nelfinavir Oral

In Depth

Generic Name: NELFINAVIR - ORAL
Pronounced: (nell-FIN-uh-veer)

Nelfinavir Oral Interactions

The effects of some drugs can change if you take other drugs or herbal products at the same time. This can increase your risk for serious side effects or may cause your medications not to work correctly. These drug interactions are possible, but do not always occur. Your doctor or pharmacist can often prevent or manage interactions by changing how you use your medications or by close monitoring.

To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval.

Some products that may interact with this drug include:

certain antiarrhythmics (amiodarone, quinidine)
certain benzodiazepines (midazolam, triazolam)
eletriptan
eplerenone
ergot alkaloids (such as dihydroergotamine, ergonovine, ergotamine, methylergonovine)
pimozide
ranolazine
rifampin
St. John's wort
certain "statin" cholesterol drugs (lovastatin, rosuvastatin, simvastatin)
certain drugs to lower acid in the stomach (proton pump inhibitors such as omeprazole)

Other medications can affect the removal of nelfinavir from your body, which may affect how nelfinavir works. Examples include rifabutin, certain anti-seizure drugs (carbamazepine, phenobarbital), other HIV drugs (such as delavirdine, indinavir, ritonavir), among others.

Nelfinavir can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include certain drugs that weaken the immune system (cyclosporine, tacrolimus, sirolimus), drugs for male sexual function problems (such as sildenafil, vardenafil), among others.

This medication may decrease the effectiveness of hormonal birth control products (such as pills, patch, ring). This effect can result in pregnancy. However, to reduce the risk of spreading HIV to others, always use barrier protections during all sexual activity. (See also Notes section.)

This document does not contain all possible drug interactions. Keep a list of all the products you use. Share the list with your doctor and pharmacist to lessen your risk for serious medication problems.