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PRAVIGARD PAC Oral

Generic Name: PRAVASTATIN/BUFFERED ASPIRIN - ORAL
Pronounced: (PRAV-uh-stat-in/BUFF-erd ASP-er-in)

PRAVIGARD PAC Oral Interactions

See also the How to Use section.

This drug should not be used with the following medication because a very serious interaction may occur:

  • mifepristone


If you are currently using this medication, tell your doctor or pharmacist before starting pravastatin/buffered aspirin.

Use caution if the following drugs are combined with pravastatin because serious side effects such as muscle injury (myopathy) infrequently could occur:

  • fibrates (e.g., gemfibrozil, fenofibrate)
  • high-dose niacin (1 gram or more per day)


Before using these medications, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • acetazolamide
  • atazanavir
  • azole antifungals (e.g., itraconazole, ketoconazole)
  • "blood thinners" (e.g., heparin, warfarin)
  • cholestyramine
  • colestipol
  • corticosteroids (e.g., prednisone)
  • cyclosporine
  • daptomycin
  • delavirdine
  • gabapentin
  • ginkgo biloba
  • levothyroxine
  • medication for gout or diabetes
  • methotrexate
  • NSAIDs (e.g., ibuprofen, naproxen)
  • quinidine
  • quinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
  • tetracycline antibiotics (e.g., tetracycline, minocycline)
  • ticlopidine
  • valproic acid


Check the labels on all your medicines because they may contain aspirin or aspirin-like NSAIDs (e.g., ibuprofen, naproxen, ketoprofen). Ask your pharmacist about the safe use of those products.

Do not start or stop any medicine without doctor or pharmacist approval.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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