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Plendil Oral

Generic Name: FELODIPINE EXTENDED-RELEASE - ORAL
Pronounced: (fell-OH-dih-peen)

Plendil Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with them first.

See also How to Use section.

Before using this medication, it is important to tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • other medications for high blood pressure
  • intravenous (IV) calcium


Also tell your doctor or pharmacist if you take drugs affecting the removal of felodipine from your system (CYP 3A4 substrates, inhibitors and inducers) such as:

  • azole antifungals (e.g., itraconazole, ketoconazole)
  • certain anti-seizure medications (e.g., carbamazepine, phenobarbital, phenytoin)
  • cimetidine
  • macrolide antibiotics (e.g., erythromycin)
  • tacrolimus


Check the labels on all your medicines (e.g., cough-and-cold products, diet aids, non-steroidal anti-inflammatory drugs or NSAIDs for pain/fever reduction) because they may contain ingredients that could increase your blood pressure. Ask your pharmacist about the safe use of these products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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