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Glimepiride Oral

Generic Name: GLIMEPIRIDE - ORAL
Pronounced: (glim-EP-er-ide)

Glimepiride Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • aspirin or aspirin-like drugs (e.g., salicylates, non-steroidal anti-inflammatory drugs - NSAIDs such as ibuprofen, phenylbutazone)
  • azole antifungals (e.g., fluconazole)
  • birth control pills
  • calcium channel blockers (e.g., diltiazem)
  • chloramphenicol
  • cimetidine
  • clofibrate
  • decongestants (e.g., pseudoephedrine)
  • diazoxide
  • diet pills
  • epinephrine
  • estrogens
  • fenugreek
  • ginseng
  • gymnema
  • isoniazid
  • MAO inhibitors (e.g., furazolidone, linezolid, moclobemide, phenelzine procarbazine, rasagiline, selegiline, isocarboxazid, tranylcypromine)
  • niacin
  • phenytoin
  • probenecid
  • rifampin
  • sulfonamides (e.g., sulfa antibiotics)
  • thyroid drugs
  • warfarin
  • "water pills" (diuretics such as hydrochlorothiazide, furosemide)


Many drugs can affect your blood sugar levels, making it more difficult to control your blood sugar. Examples include corticosteroids (such as prednisone), psychiatric medicines (such as olanzapine), fluoroquinolone antibiotics (such as ciprofloxacin), among others. Ask your doctor or pharmacist how often to check your blood sugar. Tell your doctor about the results and of any symptoms of high or low blood sugar. (See also Side Effects section.) Your doctor may need to adjust your diabetes medication, exercise program, or diet.

Beta-blocker medications (e.g., metoprolol, propranolol, glaucoma eye drops such as timolol) may prevent the fast/pounding heartbeat you would usually feel when your blood sugar level falls too low (hypoglycemia). Other symptoms of low blood sugar such as dizziness, hunger, or sweating are unaffected by these drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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