Propafenone Oral

In Depth

Generic Name: PROPAFENONE - ORAL
Pronounced: (pro-puh-FEN-own)

Propafenone Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first.

This drug should not be used with the following medications because very serious interactions may occur:

disopyramide
amiodarone
quinidine
procainamide
ibutilide
sotalol
moricizine
droperidol
bepridil
dofetilide
cisapride
pimozide
halofantrine
ranolazine
lopinavir/ritonavir
tipranavir
saquinavir

Other drugs besides propafenone and those listed above that may affect the heart rhythm (QTc prolongation in the EKG) include flecainide, tolterodine, mesoridazine, amitriptyline, levofloxacin, and erythromycin, among others. QTc prolongation can infrequently result in a serious (rarely fatal) irregular heartbeat. Consult your doctor or pharmacist for more details and for instructions on how you may minimize the risk of this effect.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting propafenone.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

digoxin
beta blockers (e.g., propranolol, metoprolol)
venlafaxine
fluoxetine
desipramine
warfarin
cimetidine
theophylline
rifampin
phenobarbital
cyclosporine
orlistat
tizanidine

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.