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METADATE CD Oral

Generic Name: METHYLPHENIDATE SUSTAINED-ACTION - ORAL
Pronounced: (meth-ill-FEN-eh-date)

METADATE CD Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks before or after treatment with this medication. In some cases, a serious, possibly fatal, drug interaction may occur. If you are currently using any of these medications, tell your doctor or pharmacist before starting this medication.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

  • "blood thinners" (e.g., warfarin)
  • clonidine
  • guanethidine
  • phenylbutazone
  • drugs that can increase blood pressure (e.g., phenylephrine)
  • anti-seizure drugs (e.g., phenobarbital, phenytoin, primidone)
  • tricyclic antidepressants (e.g., imipramine, desipramine)
  • SSRI antidepressants (e.g., fluoxetine, sertraline)


One brand of this drug may be affected by a change in the amount of acid in your stomach. Check with your pharmacist to see if the brand you are taking may be affected if you are also taking stomach acid reducers (e.g., antacids, cimetidine, omeprazole).

Also report the use of drugs which might increase seizure risk when combined with this medication such as isoniazid (INH), phenothiazines (e.g., thioridazine), theophylline, or tricyclic antidepressants (e.g., amitriptyline), among others. Consult your doctor or pharmacist for details.

Check the labels on all your medicines/herbal products (e.g., cough-and-cold products, diet aids) because they may contain ingredients that could increase your heart rate or blood pressure (e.g., pseudoephedrine, phenylephrine, ephedra/ma huang). Ask your pharmacist about the safe use of these products.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

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