Mellaril Oral

In Depth

Generic Name: THIORIDAZINE CONCENTRATE - ORAL
Pronounced: (thigh-oh-RID-uh-zeen)

Mellaril Oral Interactions

Your healthcare professionals (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

cabergoline
cisapride
duloxetine
certain SSRI antidepressants (e.g., fluoxetine, fluvoxamine, paroxetine)
pergolide
pindolol
propranolol
sibutramine

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting thioridazine.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

anticholinergic medications (e.g., belladonna alkaloids, atropine, scopolamine)
carbamazepine
guanethidine
guanadrel
lithium
medications for Parkinson's disease (e.g., levodopa, benztropine)

Many drugs besides thioridazine may affect the heart rhythm (QT prolongation), including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics (such as erythromycin), among others. Therefore, before using thioridazine, report all medications you are currently using to your doctor or pharmacist.

Also report the use of drugs which might increase seizure risk (decrease seizure threshold) when combined with this drug such as bupropion, isoniazid, haloperidol, theophylline, tramadol, or tricyclic antidepressants (e.g., amitriptyline, nortriptyline), among others.

Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (e.g., diphenhydramine), anti-seizure drugs (e.g., phenytoin), medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem), muscle relaxants, narcotic pain relievers (e.g., codeine), psychiatric medicines (e.g., chlorpromazine, risperidone, trazodone).

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