Kaletra Oral

In Depth

Generic Name: LOPINAVIR/RITONAVIR CAPSULES - ORAL
Pronounced: (low-PIN-uh-veer/rye-TAWN-uh-veer)

Kaletra Oral Interactions

See also How to Use section.

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

alfuzosin
certain non-drowsy antihistamines
cisapride
conivaptan
eletriptan
eplerenone
ergot drugs (e.g., dihydroergotamine, ergonovine, methylergonovine, ergotamine)
ivabradine
pimozide
ranolazine
rifampin
certain sedatives (midazolam, triazolam)
certain "statins" (lovastatin, simvastatin)
St John's wort
voriconazole

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting lopinavir/ritonavir.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

other HIV drugs (e.g., efavirenz, amprenavir, zidovudine, abacavir, nevirapine, atazanavir, tipranavir/ritonavir)
antidepressants (e.g., bupropion, trazodone)
atovaquone
other azole antifungals (ketoconazole, itraconazole)
"blood thinners" (e.g., warfarin)
calcium channel blockers (e.g., felodipine, nifedipine, nicardipine)
certain cancer drugs (dasatinib, lapatinib, sunitinib)
dexamethasone
drugs for erectile dysfunction (e.g., sildenafil, tadalafil, vardenafil)
fluticasone
garlic supplements
heart rhythm medication (e.g., amiodarone, bepridil, lidocaine, quinidine)
drugs that suppress the immune system (e.g., cyclosporine, tacrolimus, rapamycin)
temsirolimus
macrolide antibiotics (e.g., clarithromycin)
narcotic pain medications (e.g., methadone)
rifabutin
other sedatives (alprazolam, zolpidem)
seizure medication (e.g., phenytoin, carbamazepine, phenobarbital)
solifenacin
certain other "statins" (atorvastatin, rosuvastatin)

This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.