E-Mycin Oral

In Depth

Generic Name: ERYTHROMYCIN BASE ENTERIC - ORAL
Pronounced: (eh-rith-row-MY-sin base)

E-Mycin Oral Interactions

Your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.

This drug should not be used with the following medications because very serious interactions may occur:

eletriptan
ergot alkaloids (e.g., ergotamine, dihydroergotamine)
drugs which may affect the heart rhythm (QT prolonging drugs such as cisapride, pimozide)
ivabradine
ranolazine

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting erythromycin.

Other drugs besides erythromycin and those listed above which may affect the heart rhythm (QT prolongation in the EKG) include amiodarone, dofetilide, gatifloxacin, moxifloxacin, procainamide, propafenone, quinidine, sotalol, and thioridazine, among others. Before using erythromycin, report all medications you are currently using to your doctor or pharmacist. QT prolongation can infrequently result in serious (rarely fatal) fast/irregular heartbeat and other symptoms (e.g., severe dizziness, fainting) that require immediate medical attention. Ask your doctor or pharmacist for more details and for instructions on how you may reduce the risk of this effect.

Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of:

colchicine
digoxin
live bacterial vaccines
warfarin
certain "water pills" (potassium-wasting diuretics such as hydrochlorothiazide, furosemide)
drugs affecting liver enzymes that remove erythromycin from your body (such as azole antifungals-including itraconazole and fluconazole, rifamycins-including rifabutin, quinupristin-dalfopristin, calcium channel blockers-including diltiazem and verapamil, certain anti-seizure medicines-including carbamazepine and phenytoin and valproate)

This drug can slow down the removal of other drugs from your body by affecting certain liver enzymes. Some examples of these affected drugs include alfentanil, bromocriptine, buspirone, certain benzodiazepines (alprazolam, midazolam, triazolam), caffeine-containing drugs, cilostazol, corticosteroids (e.g., prednisone), cyclosporine, eplerenone, certain erectile dysfunction medications (sildenafil, vardenafil), eszopiclone, felodipine, certain "statin" drugs (atorvastatin, lovastatin, simvastatin), quetiapine, tacrolimus, theophylline, tolterodine, vinblastine.

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